EC Number   |
General Information |
Reference |
|---|
   2.7.7.74 | malfunction |
deleting the gene encoding the key enzyme in di-myo-inositol phosphate synthesis, CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase, abolishes di-myo-inositol phosphate synthesis. Mutants deficient in di-myo-inositol phosphate use aspartate to cope with heat stress |
708934 |
| 2.7.7.74 | physiological function |
di-myo-inositol phosphate is part of the strategy used by Thermococcus kodakarensis to cope with heat stress, and aspartate can be used as an alternative solute of similar efficacy |
708934 |
| 2.7.7.74 | physiological function |
the bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase (EC 2.7.7.74/EC 2.7.8.34) is involved in biosynthesis of bis(1L-myo-inositol) 1,3-phosphate |
721186 |
| 2.7.7.74 | physiological function |
the enzyme is involved in biosynthesis of the solute bis(1L-myo-inositol) 1,3'-phosphate, a widespread organic solute in microorganisms adapted to hot environments |
725254 |
| 2.7.7.74 | physiological function |
the enzyme is involved in synthesis of di-myo-inositol phosphate. Archaeoglobus fulgidus accumulates di-myo-inositol phosphate and diglycerol phosphate in response to heat and osmotic stresses, respectively, and the level of glycero-phospho-myo-inositol increases primarily when the two stresses are combined |
687375 |
