EC Number   |
General Information |
Reference |
|---|
   2.6.1.55 | evolution |
sequence comparisons and phylogenetic analysis of taurine:oxoglutarate aminotransferases and taurine:pyruvate aminotransferases, overview |
-, 758762 |
| 2.6.1.55 | metabolism |
BkToa is part of a gene cluster putatively involved in taurine nitrogen assimilation. In this pathway, isothionate is formed by a sulfoacetaldehyde reductase TauF, a member of the metal-dependent alcohol dehydrogenase family |
-, 758762 |
| 2.6.1.55 | more |
molecular docking reveals a role for active site residues Trp21 and Arg156, conserved in Toa enzymes, in interacting with the sulfonate group of taurine |
-, 758762 |
| 2.6.1.55 | physiological function |
taurine is thought to serve as a source of carbon, nitrogen and sulfur for certain gut bacteria, particularly for strict anaerobes residing in the nutrient-poor environment of the distal gut. Taurine aminotransferases catalyze the first step in taurine catabolism in many taurine-degrading bacteria and play an important role in bacterial taurine metabolism in the mammalian gut |
-, 758762 |
