EC Number   |
General Information |
Reference |
|---|
   2.5.1.94 | malfunction |
a chlorinase knockout mutated strain of Salinispora tropica is able to biosynthesis the fluorinated analogue of salinosporamide A, when the medium was supplemented with 5-deoxy-5-fluoroadenosine |
708247 |
| 2.5.1.94 | metabolism |
the enzyme catalyzes chlorination, the last step in the aspirochlorine pathway, modeling of the aspirochlorine biosynthesis involving an unusual Phe to Gly conversion, overview |
-, 737445 |
| 2.5.1.94 | metabolism |
the enzyme is responsible for salinosporamide-A biosynthesis |
738049 |
| 2.5.1.94 | physiological function |
key role of AclH as a chlorinase in the aspirochlorine biosynthesis. Aspirochlorine, or antibiotic A30641, is an epidithiodiketopiperazine toxin distinctive antifungal properties due to selective inhibition of protein biosynthesis produced from Aspergillus oryzae |
-, 737445 |
| 2.5.1.94 | physiological function |
SalL functions in an orthogonal manner to biological chlorination reactions to initiate the biosynthesis of a new halogenated polyketide synthase building block |
713086 |
