EC Number   |
General Information |
Reference |
|---|
   2.5.1.67 | evolution |
Artemisia tridentata chrysanthemyl diphosphate synthase is an example of an enzyme that has evolved recently from a highly specialized parent. The origins of farnesyl diphosphate synthase date back to the very beginning of cellular life, and the enzyme has perfected its ability to catalyze chain-elongation. In contrast, Artemisia tridentata chrysanthemyl diphosphate synthase has recently evolved from Artemisia tridentata diphosphate synthase, presumably by gene duplication and random mutagenesis but is still a promiscuous inefficient catalyst in comparison with farnesyl diphosphate synthase |
759401 |
| 2.5.1.67 | evolution |
the enzyme belongs to the very large family of short-chain prenyltransferases and terpene synthases |
738635 |
| 2.5.1.67 | metabolism |
chrysanthemyl diphosphate synthase is the first pathway-specific enzyme in the biosynthesis of pyrethrins |
738635 |
| 2.5.1.67 | more |
CDS should be renamed a chrysanthemol synthase utilizing dimethylallyl diphosphate as substrate |
738635 |
| 2.5.1.67 | physiological function |
biosynthesis of isoprenoid compounds |
687301 |
| 2.5.1.67 | physiological function |
chrysanthemyl diphosphate synthase is the first pathway-specific enzyme in the biosynthesis of pyrethrins, the most widely used plant-derived pesticide. The enzyme shows activity to produce diphosphates (chrysanthemyl diphosphate and lavandulyl diphosphate) and terpene alcohols (chrysanthemol and lavandulol) from dimethylallyl diphosphate |
738635 |
| 2.5.1.67 | physiological function |
overexpression of gene in micro-tom tomato results in dwarf phenotypes characterized with infertile flowers and seedless fruits. Overexpression alters the production of endogenous secondary metabolites |
723414 |
| 2.5.1.67 | physiological function |
overexpression of the CHS gene in Chrysanthemum morifoliumresults in both the emission of volatile chrysanthemol (ca. 47 pmol/h/g FW) and accumulation of chrysanthemyl-6-O-malonyl-beta-D-glucopyranoside (ca. 1.1 mM), with no detrimental phenotypic effects. Both components show independent effects against the cotton aphid (Aphis gossypii). The CHS expressing plants significantly reduce aphid reproduction, consistent with disturbance of aphid probing activities on these plants |
759925 |
| 2.5.1.67 | physiological function |
selective regulation of pyrethrin biosynthesis by the specific blend of wound induced volatiles in Tanacetum cinerariifolium |
739371 |
