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2.5.1.136
physiological function
coexpression of codon-optimized prenyltransferases PT1L and PT2 in yeast leads to the production of bitter acids. PT1L/PT2 forms and functions as a complex in membranes. PT1L catalyzes the first prenylation step, and PT2 catalyzes the two subsequent prenylation steps
741203
2.5.1.136
physiological function
PT-1 catalyzes the first transfer of dimethylallyl moiety to phloroglucinol derivatives, phlorisovalerophenone, phlorisobutyrophenone and phlormethylbutanophenone, leading to the formation of humulone and lupulone derivatives, i.e. Humulus lupulus bitter acids. PT-1 also recognizes naringenin chalcone as a flavonoid substrate to yield xanthohumol
739979
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