EC Number   |
General Information |
Reference |
|---|
   2.4.1.69 | malfunction |
absence of pgtA, wild-type O2 dependence of culmination |
704551 |
| 2.4.1.69 | malfunction |
blocking enzyme expression in arthritis synovial fibroblasts reduces endothelial cell tube formation |
735575 |
| 2.4.1.69 | malfunction |
the spontaneous G428A nonsense mutation in FUT2 provides strong but not absolute protection against symptomatic GII.4 Norovirus infection |
706426 |
| 2.4.1.69 | metabolism |
in roots, isoforms FUT4 and FUT6 genes are responsible for arabinogalactan fucosylation |
722669 |
| 2.4.1.69 | physiological function |
Biosynthesis of cell surface glycoconjugates, which play a role in infections. For example, nonsecretors are known to be virtually resistant to infection by norovirus. Inversely, women with the nonsecretor phenotype are more prone to Escherichia coli mediated recurrent urinary tract infections than secretor women. |
703927, 705209 |
| 2.4.1.69 | physiological function |
isoform Fta allows synthesis of H type 2 and H type 3 histo-blood group antigen epitopes at the cell surface. In Chinese hamster ovary cells transfected by FTA, FTA is able to synthesize H type 2 epitopes on a large set of glycoproteins |
489369 |
| 2.4.1.69 | physiological function |
Some Escherichia coli strains display human blood group antigens, so called O-antigen structures, on their cell surface to evade the immune system of the human host. alpha1,2fucosyltransferase are involved in the biosynthesis of O-antigen structures. |
-, 702217 |
| 2.4.1.69 | physiological function |
synthesis of human H-type 3 blood group structure in pharyngeal cells to secrete glycoconjugates to the nematode surface |
703885 |
| 2.4.1.69 | physiological function |
the enzyme is involved in the development of multidrug resistance of chronic myeloid leukemia cells and regulates the activity of EGFR/MAPK signaling pathway and the expression of P-glycoprotein |
736915 |
| 2.4.1.69 | physiological function |
the enzyme is responsible for synthesis of the H blood group and Lewis y antigens |
735575 |
