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EC Number	General Information	Commentary	Reference
2.4.1.148	malfunction	the triple knockout mice lack the ability to synthesize all three known isoforms of core 2 beta1,6-N-acetylglucosaminyltransferase. This multiple deficiency causes a complete absence of core 2 O-glycans in the colon	722355
2.4.1.148	physiological function	enzyme expressing tumor are more resistant to natural killer cell cytotoxicity than tumor cells with reduced enzyme expression	722416
2.4.1.148	physiological function	the enzyme synthesizes all three beta6GlcNAc branch structures found in secreted mucins	722390

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Release 2023.1 (January 2023)