EC Number   |
General Information |
Reference |
|---|
   2.3.2.27 | malfunction |
enzyme-impaired mutants show reduced sensitivity to low ambient temperature in flowering |
737249 |
| 2.3.2.27 | malfunction |
the atatl80 insertion mutant line exhibits an increased tolerance to cold stress |
735611 |
| 2.3.2.27 | malfunction |
the idf1 mutants show increased tolerance to Fe deficiency, resulting from increased IRT1 protein levels |
736984 |
| 2.3.2.27 | metabolism |
isoform Kf-1 is a short-lived protein specifically destroyed by the ubiquitin proteasome system |
690750 |
| 2.3.2.27 | metabolism |
isoform RBCK1 undergoes efficient phosphorylation by protein kinase Cbeta. The phosphorylated RBCK1 shows no self-ubiquitination activity in vitro. Overexpression of protein kinase Cbeta leads to significant increases in the amounts of intracellular RBCK1, presumably suppressing the proteasomal degradation of RBCK1 through self-ubiquitination |
693039 |
| 2.3.2.27 | metabolism |
isoform TEB4 is an ER degradation substrate itself, promoting its own degradation in a RING finger- and proteasome-dependent manner |
726899 |
| 2.3.2.27 | metabolism |
the cognate E2 co-enzymes of E3 enzyme Parkin regulate the activation, translocation and enzymatic functions of Parkin during mitochondrial quality control. UBE2D family members and UBE2L3 redundantly charge the RING-HECT hybrid ligase Parkin with ubiquitin, resulting in its initial activation and translocation to mitochondria. UBE2N primarily mediates the proper clustering of mitochondria, a prerequisite for degradation. Depletion of UBE2R1 results in enhanced Parkin translocation and clustering upon mitochondrial uncoupling |
734357 |
| 2.3.2.27 | physiological function |
AIR2 interacts with the 3-ketoacyl-CoA thiolase protein KAT1. AIR2 ubiquitinates KAT1 and promotes the degradation of KAT1 via the 26S proteasome degradation pathway. Overexpression of AIR2 in Arabidopsis improves the seed germination and increases the root length under arsenate stress conditions |
757927 |
| 2.3.2.27 | physiological function |
C3H2C3-Type RING E3 ubiquitin ligase AIRP1-overexpressing transgenic plants (35S:AtAIRP1-sGFP) are hypersensitive to exogenous abscisic acid in terms of radicle emergence, cotyledon development, root elongation, and stomatal closure. Overexpressing transgenic plants accumulate higher amounts of hydrogen peroxide in response to exogenous abscisic acid than wild-type and mutant plants. AIRP1 overexpressors are markedly tolerant to severe drought stress, as opposed to mutant plants, which are highly susceptible. The levels of drought stress-related genes and basic leucine zipper transcription factor genes are up-regulated in overexpressing plants relative to wild-type and mutant plants in response to abscisic acid |
734955 |
| 2.3.2.27 | physiological function |
C3HC4-type RING E3 ubiquitin ligase AIRP2-overexpressing transgenic and loss-of-function mutant plants exhibit hypersensitive and hyposensitive phenotypes, respectively, to abscisic acid in terms of seed germination, root growth, and stomatal movement. Overexpressing transgenic plants are highly tolerant to severe drought stress, and loss-of-function mutant alleles are more susceptible to water stress than are wild-type plants. Higher levels of drought-induced hydrogen peroxide production are detected in overexpressing mutant as compared with loss-of-function mutant plants. Abscisic acid-inducible drought-related genes are up-regulated in overexpressing and down-regulated in loss-of-function progeny. The positive effects of AIRP2 on abscisic acid-induced stress genes are dependent on SNF1-related protein kinases |
734957 |
