EC Number   |
General Information |
Reference |
|---|
   2.3.1.28 | evolution |
CAT members are currently classified into three types on the basis of their substrate specificities. Staphylococcus aureus CAT is classified as type III |
735551 |
| 2.3.1.28 | more |
homology modeling of enzyme CAT structures using the crystal structure of Escherichia coli CAT, PDB ID 3CLA, overview. Residue A138 resides on beta-sheet 7 and is located on the protein surfaces far from the active center. Although the side chains of I134, P135, and L164 surround this residue, no hydrophobic interactions are observed within 4 A. Modeling of CATA138T, overview |
735551 |
| 2.3.1.28 | more |
method development for a sensitive model system for analyzing the rapid delivery of active enzymes into various regions of the brain of Rattus norvegicus with therapeutic bioavailability, intranasal delivery of chloramphenicol acetyltransferase from Escherichia coli, a relatively large enzyme, in its active form into different regions of the brain |
736676 |
| 2.3.1.28 | physiological function |
chloramphenicol acetyltransferase type C CAT or CATC is found in Vibrio parahaemolyticus and its closely related species Vibrio alginolyticus, Vibrio antiquarius , and Vibrio diabolicus. Naturally occurring variants of CATC can confer diverse resistance levels against chloramphenicol in Escherichia coli. The enzyme kinetics of CATC variant proteins supports the diversity of their resistance phenotypes |
756925 |
| 2.3.1.28 | physiological function |
chloramphenicol resistance |
703753 |
| 2.3.1.28 | physiological function |
marker for chloramphenicol resistance |
704953 |
