EC Number |
General Information |
Reference |
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2.1.1.107 | metabolism |
the enzyme is important in the heme d1 biosynthesis, the essential prosthetic group of the dissimilatory nitrite reductase cytochrome cd1 requiring the methylation of the tetrapyrrole precursor uroporphyrinogen III at positions C-2 and C-7, pathway overview |
703663 |
2.1.1.107 | metabolism |
the enzyme is involved in the tetrapyrrole biosynthesis. Uroporphyrinogen III represents the first branch point in the pathway, where the action of enzymes such as HemE, F (N) and G results in the formation of protoporphyrin IX, a precursor of modified tetrapyrroles such as haem and chlorophyll. Alternatively, uroporphyrinogen III can undergo a S-adenosylmethionine-dependent transmethylation positions 2 and 7, by CysG, Met1p or CobA depending on the organism, to generate precorrin-2, a highly unstable yellow dipyrrocorphin, overview |
696120 |
2.1.1.107 | metabolism |
uroporphyrinogen III synthase/methyltransferase is a key bifunctional enzyme in the biosynthesis of cobalamin and other tetrapyrrols |
-, 714579 |
2.1.1.107 | physiological function |
enzyme overexpression confers resistance of the Escherichia coli cells to potassium tellurite that inhibits cell growth |
734345 |
2.1.1.107 | physiological function |
overexpression of UPM1 signals higher nitrite reductase (NII) and sulfite reductase gene and gene product expression. Increased NII expression regulates and enhances the transcript and protein abundance of nitrate reductase. Due to higher N and S assimilation in these plants, total protein content increases. Consequently, chlorophyll biosynthesis increases and upregulates photosynthetic electron transport and carbon assimilation. In the antisense plants, the transcript abundance, and protein content of nitrite reductase (NII) and sulfite reductase decrease, resulting in reduced total protein and chlorophyll content |
756824 |
2.1.1.107 | physiological function |
the role of SUMT methyltransferase in tellurite(ate) detoxification is not related to tellurium volatilization |
-, 706702 |