EC Number   |
General Information |
Reference |
|---|
   2.1.1.103 | malfunction |
Arabidopsis pmeamt T-DNA mutant (atpmeamt) lacks transcripts associated with PMEAMT but has no overt phenotype. The leaf membrane phospholipid profiles show a greater content of PtdMEA as the 34:3 lipid molecular species in atpmeamt plants relative to wild type |
719882 |
| 2.1.1.103 | malfunction |
disruption of enzyme activity results in severe defects in important cellular processes such as development, replication, survival and sexual maturation and differentiation |
719039 |
| 2.1.1.103 | malfunction |
inhibition of enzyme biosynthesis leads to necrotic lesions in leaves, multiple inflorescences, sterility in the flower, and early flowering in short day conditions |
734005 |
| 2.1.1.103 | malfunction |
knock-out of the PMT gene encoding the phosphoethanolamine methyltransferase enzyme completely abrogates the biosynthesis of phosphatidylcholine via the serine-decarboxylase-phosphoethanolamine-methyltransferase pathway, loss of PMT results in significant defects in parasite growth, multiplication, and viability, suggesting that this gene plays an important role in the pathogenesis of intraerythrocytic Plasmodium parasites |
698812 |
| 2.1.1.103 | malfunction |
parasites lacking the enzyme are incapable of producing mature gametocytes and are not transmitted to mosquitoes |
735175 |
| 2.1.1.103 | metabolism |
the enzyme has a central role in phosphatidylcholine biosynthesis via the methylation pathway and plays a role in cell division and inflorescence meristem |
734005 |
| 2.1.1.103 | physiological function |
enzyme can rescue a choline auxotroph of yeast |
719882 |
| 2.1.1.103 | physiological function |
isoform NMT1 is essential for normal growth and salt tolerance. The NMT1 mutant displays a short root phenotype under normal growth conditions and hypersensitivity, as determined by root length, under salt-stress conditions |
757185 |
| 2.1.1.103 | physiological function |
loss of function of DPR2/PEAMT1 affects root stem cell niche, division zone, elongation and differentiation zone. PIN-FORMED (PIN) protein abundance, PIN2 polar distribution and general endocytosis are impaired in the root tip of the mutant. Excess hydrogen peroxide and auxin accumulate in the elongation and differentiation zone, leading to root apical meristem consumption by accelerating cell differentiation |
757824 |
| 2.1.1.103 | physiological function |
the enzyme is essential for normal growth and development |
734288 |
