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Results 1 - 7 of 7
EC Number General Information Commentary Reference
Show all pathways known for 1.5.8.4Display the word mapDisplay the reaction diagram Show all sequences 1.5.8.4malfunction rare natural mutation H109R, causes dimethylglycine dehydrogenase deficiency leading to increased blood and urinary dimethylglycine concentrations 742499
Show all pathways known for 1.5.8.4Display the word mapDisplay the reaction diagram Show all sequences 1.5.8.4metabolism the enzyme takes part in choline degradation, one-carbon metabolism and electron transfer to the respiratory chain 742499
Show all pathways known for 1.5.8.4Display the word mapDisplay the reaction diagram Show all sequences 1.5.8.4metabolism the phosphorylation of Akt-308/473 is significantly suppressed when the enzyme is overexpressed 743378
Show all pathways known for 1.5.8.4Display the word mapDisplay the reaction diagram Show all sequences 1.5.8.4physiological function dimethylglycine dehydrogenase expression suppresses metastasis through the Akt signaling pathway 743378
Show all pathways known for 1.5.8.4Display the word mapDisplay the reaction diagram Show all sequences 1.5.8.4physiological function DMGDH suppresses migration, invasion and metastasis both in vitro and in vivo. In a DMGDH over-expressing cell line, the phosphorylation of Akt-308/473 is significantly suppressed 743378
Show all pathways known for 1.5.8.4Display the word mapDisplay the reaction diagram Show all sequences 1.5.8.4physiological function during the process of intestine regeneration, there are significant differences in metabolism between regenerative intestines at 3, 7, and 14 days post evisceration and normal intestines. Genes encoding betaine-aldehyde dehydrogenase, betaine-homocysteine S-methyltransferase 1, and dimethylglycine dehydrogenase are differentially expressed to regulate the levels of betaine and N,N-dimethylglycine during intestine regeneration 764528
Show all pathways known for 1.5.8.4Display the word mapDisplay the reaction diagram Show all sequences 1.5.8.4physiological function the enzyme suppresses metastasis in hepatocellular carcinoma 743378
Results 1 - 7 of 7