EC Number   |
General Information |
Reference |
|---|
    1.3.1.32 | evolution |
mutagenesis studies show that His172 and Lys238 are essential for the catalytic activity of the enzyme (PcpE). However,the mutation of His236 to an alanine can increase the catalytic efficiency (kcat/Km) of PcpE by more than 2fold, implying that PcpE is still in an early stage of molecular evolution. The enzyme (PcpE) exhibits an extremely low but detectable level of alcohol dehalogenase activity toward ethanol and supports the notion that it is evolved from an iron-containing alcohol dehydrogenase |
-, 763715 |
| 1.3.1.32 | malfunction |
cells bearing a disrupted hadD gene do not grow on plates with 2,4,6-TCP |
724600 |
| 1.3.1.32 | metabolism |
last enzyme in the pentachlorophenol biodegradation pathway |
-, 763715 |
| 1.3.1.32 | metabolism |
the enzyme is involved in degradation of hydroxyquinol |
762650 |
| 1.3.1.32 | physiological function |
maleylacetate reductase is responsible for 2,4,6-trichlorophenol degradation in Ralstonia pickettii DTP0602 |
724600 |
