EC Number |
General Information |
Reference |
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1.2.1.84 | malfunction |
enzyme mutation has significant effects on reducing cutin monomers and internal lipids, and altering the composition of cuticular wax in anthers. Moreover, loss of function of the enzyme significantly affects the expression of its four paralogous genes and five cloned lipid metabolic male-sterility genes in maize |
763327 |
1.2.1.84 | malfunction |
in waterproof mutant embryos the formation of the outermost tracheal cuticle sublayer, the envelope is disrupted and the hydrophobic tracheal coating is damaged |
742343 |
1.2.1.84 | malfunction |
knockdown of isoforms FAR5, 6, 11 or 15 is lethal and causes a slender body shape, while the old cuticles of the respective animals remain attached to the abdomen or failed to split open from the nota. Knockdown of isoform FAR9 results in a phenotype, with a smooth body surface and a decrease in cuticular hydrocarbon amounts. Knockdown of isoforms FAR1, 4, 5, 6, 8, 9, 11 and 13 additionally results in female adult infertility |
763545 |
1.2.1.84 | metabolism |
degradation of Far1 is accelerated by inhibiting dynamin-, Src kinase-, or flotillin-1-mediated endocytosis without increasing the cellular level of plasmalogens. Far1 is stabilized by sequestering cholesterol with nystatin |
741434 |
1.2.1.84 | metabolism |
fatty acyl-CoA reductases (FARs) are key enzymes involved in fatty alcohol synthesis |
743047 |
1.2.1.84 | metabolism |
isoform FAR1 is involved in the biosynthesis of primary alcohols in the leaf blades of Aegilops tauschii |
763101 |
1.2.1.84 | metabolism |
isoform FAR2 is involved in the biosynthesis of primary alcohols in the leaf blades of Aegilops tauschii |
763101 |
1.2.1.84 | metabolism |
isoform FAR3 is involved in the biosynthesis of primary alcohols in the leaf blades of Aegilops tauschii |
763101 |
1.2.1.84 | metabolism |
isoform FAR4 is involved in the biosynthesis of primary alcohols in the leaf blades of Aegilops tauschii |
763101 |
1.2.1.84 | metabolism |
isoform FAR6 is involved in the biosynthesis of primary alcohols in the leaf blades of Aegilops tauschii |
763101 |