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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.59physiological function the first step in thienodolin biosynthesis is catalyzed by a tryptophan 6-halogenase, and the last step is the formation of a carboxylic amide group catalyzed by an amidotransferase. Gene ThdH encodes tryptophan 6-halogenase, which catalyzes the regioselective chlorination of tryptophan to 6-chlorotryptophan. This flavin-dependent halogenase requires the participation of a flavin reductase, which is encoded by thdF. A gene deletion mutant of tryptophan 6-halogenase ThdH is not able to produce thienedolin -, 744696
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.59physiological function transformation of the pyrrolnitrin producer Pseudomonas chlororaphis ACN with a plasmid containing the tryptophan 6-halogenase gene leads to the formation of the aminopyrrolnitrin derivative 3-(2'-amino-4'-chlorophenyl)pyrrole -, 744198
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