EC Number |
General Information |
Reference |
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1.13.11.8 | evolution |
protocatechuate 4,5-dioxygenase (LigAB) from Sphingobium sp. strain SYK-6 is the defining member of the type II extradiol dioxygenase superfamily, a.k.a. PCA dioxygenase superfamily or PCADSF, computational docking and sequence comparisons of the enzyme with PCA dioxygenase superfamily LigAB enzymes |
741768 |
1.13.11.8 | metabolism |
catabolic pathway for protocatechuate in strain E6 and gene organization of the PCA45 pathway genes, overview |
-, 710947 |
1.13.11.8 | metabolism |
the enzyme is involved in the catabolic degradation pathway of protocatechuate, 2-pyrone-4,6-dicarboxylate is a normal intermediate in the meta fission degradative pathway of protocatechuate |
717710 |
1.13.11.8 | metabolism |
the enzyme takes part in the protocatechuate (PCA) 4,5-cleavage pathway, one of the key metabolic routes for degradation of various aromatic compounds, e.g lignin-derived low-molecular-weight aromatic compounds, phthalate isomers, and fluorene |
742019 |
1.13.11.8 | more |
PCA 4,5-dioxygenase is essential for growth of strain E6 on protocatechuate, disruption of pmdB in E6, which code for the beta-subunit of PCA 4,5-dioxygenase results in a growth defect on protocatechuate, while inactivation of pmdBII does not affect the growth |
-, 710947 |
1.13.11.8 | physiological function |
the enzyme plays a key aromatic ring-opening role in the metabolism of several lignin derived aromatic compounds |
741768 |
1.13.11.8 | physiological function |
transcriptional regulation of the Comamonas-type enzyme, overview |
742019 |
1.13.11.8 | physiological function |
transcriptional regulation of the Sphingobium-type enzyme, overview |
742019 |