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1.1.1.369
physiological function
enzyme forms part of the iol operon for myo-inositol catabolism, consisting of 10 iol genes, iolA to iolJ. iolG corresponds to idh, encoding myo-inositol 2-dehydrogenase. Disruption of the iol promoter prevents synthesis of the iol transcript as well as that of Idh. Immediately upstream of the iol operon, two genes iolR and iolS with divergent orientations to the iol operon are localized. Disruption of iolR but not iolS causes constitutive synthesis of the iol transcript and Idh. The iolRS genes are cotranscribed from another inositol-inducible promoter
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