EC Number   |
General Information |
Reference |
|---|
    1.1.1.343 | malfunction |
compared to the wild type, the deletion mutant strain DELTAgndA does not grow, but growth is fully recovered by in-trans complementation with gndA. Growth of the deletion mutant can also be recovered by the addition of uridine to the medium, suggesting that Haloferax volcanii can circumvent the metabolic block for pentose phosphate formation via the oxidative pentose phosphate pathway by converting uridine to ribose-5-phosphate, catalyzed by uridine phosphorylase and phosphopentomutase |
-, 729742 |
| 1.1.1.343 | malfunction |
gntZ mutants exhibit no detectable phenotype on glucose |
-, 655880 |
| 1.1.1.343 | malfunction |
gntZ mutants grow normally on glucose |
-, 655880 |
| 1.1.1.343 | metabolism |
the enzyme commits hexoses to the pentose phosphate pathway |
-, 723775 |
| 1.1.1.343 | physiological function |
GntZ does not contribute to pentose phosphate pathway fluxes during growth on glucose |
-, 655880 |
| 1.1.1.343 | physiological function |
the enzyme catalyzes an important reaction in the oxidative pentose phosphate pathway, producing a ribose precursor essential for nucleotide and nucleic acid synthesis |
-, 761070 |
| 1.1.1.343 | physiological function |
the enzyme is essential for the biosynthesis of pentose phosphates from glucose-6-phosphate during growth of Haloferax volcanii on glucose as growth substrate |
-, 729742 |
