EC Number   |
General Information |
Reference |
|---|
  1.1.1.326 | evolution |
the enzyme belongs to the short-chain dehydrogenase enzyme superfamily |
748561 |
| 1.1.1.326 | evolution |
ZSD1 is a member of the short-chain dehydrogenase/reductase superfamily, SDR, and shares high identities with other plant SDRs involved in secondary metabolism, stress responses and phytosteroid biosynthesis |
717593 |
| 1.1.1.326 | metabolism |
ZSD1 is an alcohol dehydrogenase capable of catalyzing the final step of zerumbone biosynthesis, but ZSD1 is also be involved in other biological processes |
717593 |
| 1.1.1.326 | more |
the enzyme contains an active site sequence 155Y-X-X-X-K159, Ser142 completes the Ser-Tyr-Lys triad responsible for the catalysis of ZSD1 |
717593 |
| 1.1.1.326 | physiological function |
the enzyme catalyzes the biosynthesis of zerumbone, a monocyclic sesquiterpenoid ketone with potential anti-inflammatory and anti-carcinogenic effects and also potential applications in obesity prevention and treatment |
748561 |
| 1.1.1.326 | physiological function |
ZSD1 is involved in secondary metabolism, stress responses and phytosteroid biosynthesis |
717593 |
