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Results 1 - 4 of 4
EC Number
General Information
enzyme silencing clearly inhibits proliferation of JEG-3 cells, significantly induces cell apoptosis and reduces the production of progesterone and human chorionic gonadotropin
physiological function
Methanococcus maripaludis Mm900 is facultatively selenium-dependent with a single pathway of Sec-tRNASec formation. Seelenocysteine formation is abolished upon individually deleting the genes encoding selenophosphate synthetase, phosphoseryl-tRNASec kinase, or SepSecS. The resulting mutant strains can no longer grow on formate while growth with H2 + CO2 remains unaffected. Deletion of the phosphoseryl-tRNASec kinase and SepSecS genes is not possible unless the selenium-free [NiFe]-hydrogenases Frc and Vhc are expressed
physiological function
the enzyme is dispensable for the parasite survival
physiological function
the enzyme significantly affects proliferation, apoptosis and hormone secretion of human trophoblast cells
Results 1 - 4 of 4