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Results 1 - 10 of 10
EC Number
General Information
Commentary
Reference
malfunction
knocking down enzyme receptor in fibroblasts cells significantly reduces HSV-1 entry and glycoprotein D binding to cells
physiological function
3-O-sulfotransferase-3 isoform mediates Herpes simplex virus type 1 entry and spread
physiological function
3-OST3A exerts dual activities acting as tumor-suppressor in MCF-7 and MDA-MB-231 cells, or as an oncogenic factor in SKBR-3 cells
physiological function
CHO-K1 cells expressing 3-OST-3 isoform induce membrane protrusions during herpes simplex virus type-1 entry. Enzyme expression is associated with enhanced filopodia induction; heparan sulfate proteoglycans modified by zebrafish encoded glucosaminyl 3-O sulfotransferase-3 generate a receptor for herpes simplex virus type-1 entry and spread
physiological function
isoform 3-OST-3 mediates herpes simplex virus-1 entry and spread
physiological function
isoform HS3ST3B1 positively contributes to acute myeloid leukemia progression. The enzyme increases vascular endothelial growth factor expression and release by leukemia cells and promotes the activation of the Notch-1-Jagged-1, PI3K-AKT and ERK pathways
physiological function
the enzyme is a epithelial-mesenchymal transition inducer in pancreatic cancer. Overexpression of isoform 3-OST-3B1 upregulates Snail expression and triggers its nuclear translocation. The enzyme promotes in vivo angiogenic response
physiological function
the enzyme is involved in bone marrow mesenchymal stromal cell differentiation
physiological function
the enzyme plays a role in pre-eclampsia-associated placental dysfunction
physiological function
the enzyme shows a potent inhibitory effect on hepatitis B virus replication and protein expression
Results 1 - 10 of 10