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when silencing the enzyme, an important accumulation of 4alpha-methyl-DELTA7-sterols is found, with no change in the levels of 4,4-dimethylsterols
enzyme expression in a yeast erg25 ergosterol auxotroph, lacking sterol-4alpha-methyl oxidase activity, restores growth and endogenous ergosterol synthesis
the enzyme is involved in the removal of the second C4-methyl group of phytosterol precursors
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