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physiological function
CYP3A4 is a major enzyme involved in the oxidation of 1,8-cineole by human liver microsomes, as there is a good correlation between CYP3A4 contents and 1,8-cineole 2-hydroxylation activities in liver microsomes of eighteen human samples and of various recombinant human P450 enzymes examined, CYP3A4 has the highest activities for 1,8-cineole 2-hydroxylation
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