EC Number   |
General Information |
Reference |
|---|
   1.13.99.1 | physiological function |
kidney-specific expression of myo-inositol oxygenase in acute kidney injury |
-, 744739 |
| 1.13.99.1 | physiological function |
MIOX is a renal specific, proximal tubule protein that is increased in plasma ofanimals and critically ill patients with acute kidney injury, AKI. MIOX preceds the elevation in SCr by approximately two days in human patients |
744739 |
| 1.13.99.1 | physiological function |
myo-inositol oxygenase (MIOX) is a tubular enzyme that catabolizes myo-inositol to D-glucuronate via the glucuronate-xylulose pathway |
745357 |
| 1.13.99.1 | physiological function |
myo-inositol oxygenase (MIOX) is a tubular-specific enzyme, that modulates redox imbalance and apoptosis in tubular cells in diabetes, role of MIOX in perturbation of mitochondrial quality control, including mitochondrial dynamics and autophagy/mitophagy, under high-glucose ambience or a diabetic state, overview |
745184 |
| 1.13.99.1 | physiological function |
overexpression of the PeaT1 elicitor gene from Alternaria tenuissima in Oryza sativa improves drought tolerance in rice plants via interaction with a myo-inositol oxygenase. In PeaT1-overexpressing (PeaT1OE) plants, abscisic acid and chlorophyll contents significantly increase, while the malondialdehyde (MDA) content decreases compared with the wild-type plants. Transcript levels of drought-responsive genes, including OsAM1, OsLP2, and OsDST, are prominently lower in the PeaT1OE plants. In contrast, expression levels of genes encoding positive drought stress regulators including OsSKIPa, OsCPK9, OsNAC9, OSEREBP1, and OsTPKb are upregulated in PeaT1OE plants. OsMIOX is highly expressed in PeaT1OE plants during the drought treatment |
745009 |
| 1.13.99.1 | physiological function |
positive function of enzyme GsMIOX1a in the alkaline response in Glycine soja plants, GsMIOX1a gene positively regulates plant tolerance to alkaline stress. Other soybean varieties, including Glycine soja 07256, Glycine soja 50109, Glycine max Suinong 28 and Glycine max Hefeng 55. Glycine max Suinong 28 and Glycine max Hefeng 55 are Chinese soybean cultivars that exhibit much lower adaptability to stress compared to Glycine soja 07256. Glycine soja 50109 is also a kind of wild soybean but is not reported to be alkaline resistant |
-, 746190 |
| 1.13.99.1 | physiological function |
start of catabolism of carbon skeleton of cell-signaling inositol polyphosphates and phosphoinositides |
697532 |
| 1.13.99.1 | physiological function |
the enzyme myo-inositol oxygenase is the key enzyme of a pathway leading from myo-inositol to UDP-glucuronic acid. The primary function of myo-inositol oxygenase for syncytium development after infection with Heterodera schachtii is probably not the production of UDP-glucuronic acid as a precursor for cell wall polysaccharides, but the reduction of myo-inositol levels and thereby a reduction in the galactinol level to avoid the induction of defence-related genes |
-, 745898 |
| 1.13.99.1 | physiological function |
the importance of MIOX in syncytium development is the removal of excess myo-inositol from syncytia |
728381 |
