EC Number |
Expression |
Reference |
---|
6.2.1.16 | more |
specificity protein 1 (Sp1) regulates gene expression of AACS in Neuro-2a cells, investigation of promoter activity of AACS, overview |
744249 |
6.2.1.16 | more |
the human AACS promoter is a PPARgamma target gene. Nuclear receptor PPARgamma is recruited to the AACS promoter by direct interaction with Sp1 |
702149 |
6.2.1.16 | up |
peroxisome-proliferator-activated receptor gamm, PPARgamma, induces AACS and adipogenesis. A PPAR-responsive element, PPRE-independent mechanism might be involved in PPARgamma-mediated AACS gene expression. PPARgamma-dependent activation of the human AACS gene is mediated by the GC boxes |
702149 |
6.2.1.16 | up |
specificity protein 1 (Sp1) binds to the Sp1 binding site on the promoter region of AACS. Overexpression of Sp1 increases AACS mRNA levels |
744249 |
6.2.1.16 | up |
treatment of hepatocytes with U18666A results in the upregulation of AACS gene expression |
-, 720477 |