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EC Number	Expression	Commentary	Reference
4.2.2.7	down	phosphate suppresses the enzyme production in cells, enzyme production is also reduced by potassium nitrate, maltose, mannose, and especially by sucrose, overview	693981
4.2.2.7	up	heparin induces the enzyme in cells, enzyme production is also upleveled by addition of N-acetyl D-glucosamine, glutaric acid, mannitol, arabinose, pyridoxine, diammonium biphosphate, ammonium nitrate, and especially by chitin, slight enhancement by L-leucine, L-glutamine, and L-histidine, overview	693981
4.2.2.7	up	inducible heparinase	-, 713782

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Release 2023.1 (January 2023)