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EC Number	Expression	Commentary	Reference
4.1.3.25	down	substantially downregulated in acetate-grown cells	-, 746828
4.1.3.25	up	high activities of itaconyl-CoA hydratase in cell extracts of itaconate-grown Paraburkholderia xenovorans	-, 746828
4.1.3.25	up	upregulated at both transcription and protein levels When 40 g/l of exogenous itaconic acid is added into the medium at the beginning of fermentation	-, 746855

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Release 2023.1 (January 2023)