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3.4.22.40
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interferon-gamma significantly reduces the expression of bleomycin hydrolase. The enzyme activity and expression are markedly decreased in atopic dermatitis lesional and non-lesional skin (to 27.1 and 8.8%, respectively)
717865
3.4.22.40
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interleukin-4 does not show any direct effect on bleomycin hydrolase expression
717865
3.4.22.40
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bleomycin hydrolase expression is up-regulated via IRF-1/2, MZF-1 and Sp-1. mRNA is up-regulated in keratinocytes when cultured at high calcium concentration (6.8fold)
717865
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