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EC Number
Expression
Commentary
Reference
2.7.8.27
down
enzyme inhibition or down-regulation of SMS1 expression by siRNA selectively inhibits the proliferation of Bcr-abl-positive cells
722907
2.7.8.27
more
both isoforms SMSL1 and SMSL2 are highly expressed in adults
761250
2.7.8.27
up
isoform SMS1 is highly elevated (approximately 10fold) in K-562 chronic myelogenous leukemia cells
722907
2.7.8.27
up
lipopolysaccharide induction analyzed in an ALI mouse model, compared with the control group, the mRNA and protein levels of CD14 are significantly increased, and the activity of SMS and expression of SMS2 are significantly upregulated in the model group
739087
2.7.8.27
up
treatment with bacterial lipopolysaccharide up-regulates the expression and activity of sphingomyelin synthases
760628
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