EC Number   |
Expression |
Reference |
|---|
   2.7.11.30 | down |
down-regulation of ALK1 in LX-2 cells by the herbal compound Cpd861, cells are treated with TGF-beta1 (5 ng/ml) Cpd861 (0.1 mg/ml), TGF-beta1 (5 ng/ml) plus Cpd861 (an extract of 10 herbs traditionally applied as chinese medicine, 5 ng/ml) for 24 h to investigate the effect of Cpd861 on the TGF-beta1/ALK1 pathway |
706906 |
| 2.7.11.30 | down |
exposure to monocrotaline and chronic hypoxia leads to a reduction in the expression of BMPR-II mRNA in rat lungs by day 21 |
703244 |
| 2.7.11.30 | more |
(1'R,5'S,6'S)-2-(3',5'-dibromo-1',6'-dihydroxy-4'-oxocyclohex-2'-enyl) acetonitrile has no effects on TGF-beta receptor synthesis |
740796 |
| 2.7.11.30 | more |
in endoglin +/- mice, ACVRL1 is expressed in small regions of the distal arteries where endoglin is below detectable limits, co-expression of ACVRL1 and endoglin and associated pSmad1/5/8 signalling in the endothelial cells of distal arterioles |
705441 |
| 2.7.11.30 | more |
reduction of endogenous ALK1 expression significantly attenuates BMP9-mediated phosphorylation of Smad1/5 and Smad2 |
704485 |
| 2.7.11.30 | more |
the ALK1 gene is constitutively expressed in LX-2 cells and TGF-beta1 does not further increase its expression |
706906 |
| 2.7.11.30 | up |
apoptosis activates isoforms RIPK1 and RIPK3 |
762408 |
| 2.7.11.30 | up |
enzyme expression is increased after treatment with polyinosinic:polycytidylic acid (5.99fold 0.05 mg/ml after 4 h), peptidoglycan from Staphylococcus aureus (5.36fold at 0.05 mg/ml after 2 h), and challenge with Edwardsiella tarda (3.1fold after 2 h). The enzyme is highly expressed in earlier embryonic development, and this pattern continues to the blastula stage and reaches the peak in the morula stage. Then, the enzyme expression decreases in subsequent stages, however, it increases again in the hatching stage |
761110 |
| 2.7.11.30 | up |
the enzyme is induced by salt and drought stresses and by abscisic acid, its expression increases in both roots and leaves. Abascisic acid induction of GsSRK expression does not mimic the induction obtained by salt and drought stresses, particularly in roots, which strongly indicates that GsSRK regulates plant tolerance to salt and drought stresses through an abscisic acid-independent pathway |
740900 |
