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EC Number
Expression
Commentary
Reference
2.7.1.154
down
PI3KC2alpha mRNA is downregulated in islets from type 2 diabetic patients compared to nondiabetic individuals
761670
2.7.1.154
down
PI3KCb and PI3KC2a mRNA levels are significantly lower in insulin/wortmannin group than those in single insulin group. Single wortmannin treatment shows no differences on the mRNA level of all PI3Ks, but wortmannin pretreatment significantly reduces insulin-induced upregulation on the mRNA level of PI3KCb and PI3KC2a
761194
2.7.1.154
down
PI3KCb and PI3KC2a mRNA levels are significantly lower in insulin/wortmannin group than those in single insulin group. Single wortmannin treatment shows no differences on the mRNA level of all PI3Ks, but wortmannin pretreatment significantly reduces insulin-induced upregulation on the mRNA level of PI3KCb and PI3KC2a in insulin/wortmannin group than those in single insulin group
761194
2.7.1.154
up
insulin incubation also significantly upregulates the mRNA expression of PI3KCb and PI3KC2a
761194
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