EC Number   |
Expression |
Reference |
|---|
   2.7.1.138 | down |
all-trans retinoic acid inhibits ceramide kinase transkription during neuronal differentiation of a human neuroblastoma cell line SH-SY5Y, inhibition of the transcriptional activity of the 5'-promoter of ceramide kinase. Retinol does not reduce CERK protein and mRNA level |
699665 |
| 2.7.1.138 | down |
Cerk is rapidly upregulated in tumor cells following HER2/neu downregulation or treatment with adriamycin |
737976 |
| 2.7.1.138 | down |
expression of the enzyme, after 24 h of treatment with 1alpha,25-dihydroxyvitamin D3 or its analogue ZK191784, is reduced by approximately 40 and 60%, respectively |
723271 |
| 2.7.1.138 | more |
ceramide kinase expression shows no association with age, lymph node status and tumor size |
699089 |
| 2.7.1.138 | more |
DCERK protein is expressed during all developmental stages |
701002 |
| 2.7.1.138 | up |
higher expression in estrogen receptor negative breast tumors, gene expression of ceramide kinase is associated with prognosis in breast cancer, high ceramide kinase expression is correlated with ErbB2 status |
699089 |
