EC Number   |
Expression |
Reference |
|---|
   2.3.1.22 | down |
basal and fasting-induced expression of Mogat1 is markedly diminished in the liver of mice lacking the transcription factor PPARalpha |
757379 |
| 2.3.1.22 | down |
marked weight loss following gastric bypass surgery is associated with a significant reduction in MOGAT2 and MOGAT3 expression |
720180 |
| 2.3.1.22 | down |
the infection with a short hairpin RNA-adenovirus construct lowers the lysophosphatidylglycerol acyltransferase 1 expression in diabetic (db/db) mice compared to a control virus infection in a dose-dependent manner, causing a marked reduction in serum triacylglycerol and cholesterol levels, and a significant increase in hepatic cholesterol levels |
705006 |
| 2.3.1.22 | up |
diabetes, obesity, and lactation induce liver monoacylglycerol acyltransferase activity in rodents that is correlated with increased fat absorption |
701625 |
| 2.3.1.22 | up |
expression of MGAT1 is robustly induced during adipocyte differentiation and its expression is suppressed in fat of genetically-obese mice |
757377 |
| 2.3.1.22 | up |
expression of MGAT1 is robustly induced during adipocyte differentiation and its expression is suppressed in metabolically abnormal obese human subjects |
757377 |
| 2.3.1.22 | up |
hepatic expression of Mogat1 is significantly increased in the liver of fasted mice compared with mice given ad libitum access to food |
757379 |
| 2.3.1.22 | up |
hepatic LPGAT1 expression in diabetic (db/db) mice is 2fold higher than in control (db/m), consistent with 1.5fold higher hepatic monoacylglycerol acyltransferase activity |
705006 |
| 2.3.1.22 | up |
isozyme MGAT1 is highly induced up to 10fold by peroxisome proliferator-activated receptor gamma, PPARgamma, overexpression in human primary hepatocytes |
735610 |
