EC Number   |
Expression |
Reference |
|---|
    2.1.1.2 | more |
no transcript of GAMT is detected from fertilized egg to blastula stage |
686291 |
| 2.1.1.2 | up |
both RNA and protein levels of GAMT are increased in a p53-dependent manner after various inducers of genotoxic stress (etoposide, H2O2, and gamma-irradiation), glucose deprivation induces GAMT in a p53-dependent manner, GAMT mRNA and protein are increased in several tissues of glucose-deprived p53 wild-type mice while remaining unchanged in the same tissues of p53 null mice |
705726 |
| 2.1.1.2 | up |
GAMT induction in response to DNA damage is dependent upon p53, GAMT also shows p53-dependent induction in response to exogenously expressed p53 and genotoxic stress, metabolic stress induces GAMT expression to regulate creatine levels in a p53-dependent manner |
705727 |
| 2.1.1.2 | up |
GAMT mRNA expression is relatively low until 34 days gestation, in the fetal liver GAMT mRNA and protein expression are also relatively low until 34-37 days gestation, between mid-gestation and term neither GAMT mRNA nor protein can be detected in the placenta |
702888 |
| 2.1.1.2 | up |
high expression in tumor cells |
703632 |
