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Results 1 - 10 of 60 > >>
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EC Number BRENDA No. Title Journal Volume Pages Year Organism PubMed ID
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.47753422 Bacterial killing by complement requires membrane attack complex formation via surface-bound C5 convertases EMBO J. 38 e99852 2019 Homo sapiens 30643019
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.47752433 C5 convertase blockade in membranoproliferative glomerulonephritis a single-arm clinical trial Am. J. Kidney Dis. 74 224-238 2019 Homo sapiens 30929851
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.47753663 Functional characterization of alternative and classical pathway C3/C5 convertase activity and inhibition using purified models Front. Immunol. 9 1691 2018 Homo sapiens 30083158
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.47753082 Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes BMC Biol. 13 93 2015 Homo sapiens 26552476
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.47755170 Neisseria heparin binding antigen is targeted by the human alternative pathway C3-convertase PLoS ONE 13 e0194662 2018 Homo sapiens 29579105
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.47754745 The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a novel targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer mouse models Mol. Immunol. 105 150-164 2019 Homo sapiens 30513451
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.47701017 3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase Proc. Natl. Acad. Sci. USA 106 882-887 2009 Homo sapiens 19136636
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.4736600 A conserved element in the serine protease domain of complement factor B J. Biol. Chem. 273 25996-26000 1998 Homo sapiens 9748277
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.47707855 A novel approach to preventing the hemolysis of paroxysmal nocturnal hemoglobinuria: both complement-mediated cytolysis and C3 deposition are blocked by a monoclonal antibody specific for the alternative pathway of complement Blood 115 2283-2291 2010 Homo sapiens 20068220
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.47717849 Access to the complement factor B scissile bond is facilitated by association of factor B with C3b protein J. Biol. Chem. 286 35725-35732 2011 Homo sapiens 21862585
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