EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   3.4.21.43 | 753663 |
Functional characterization of alternative and classical pathway C3/C5 convertase activity and inhibition using purified models |
Front. Immunol. |
9 |
1691 |
2018 |
Homo sapiens |
30083158 |
| 3.4.21.43 | 754745 |
The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a novel targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer mouse models |
Mol. Immunol. |
105 |
150-164 |
2019 |
Homo sapiens |
30513451 |
| 3.4.21.43 | 652494 |
A corresponding tyrosine residue in the C2/factor B type A domain is a hot spot in the decay acceleration of the complement C3 convertases |
J. Biol. Chem. |
278 |
52386-52391 |
2003 |
Homo sapiens |
14561755 |
| 3.4.21.43 | 81408 |
A new function of the activated third component of complement: binding to C5, an essential step for C5 activation |
Immunology |
34 |
29-40 |
1978 |
Homo sapiens |
624565 |
| 3.4.21.43 | 81415 |
A novel bifunctional chimeric complement inhibitor that regulates C3 convertase and formation of the membrane attack complex |
J. Immunol. |
155 |
4135-4138 |
1995 |
Homo sapiens |
7594566 |
| 3.4.21.43 | 698871 |
Activation of complement component C5: comparison of C5 convertases of the lectin pathway and the classical pathway of complement |
J. Biol. Chem. |
283 |
7853-7863 |
2008 |
Homo sapiens |
18204047 |
| 3.4.21.43 | 732572 |
Aurin tricarboxylic acid self-protects by inhibiting aberrant complement activation at the C3 convertase and C9 binding stages |
Neurobiol. Aging |
34 |
1451-1461 |
2013 |
Homo sapiens |
23177218 |
| 3.4.21.43 | 708190 |
Complement activation pathways in murine immune complex-induced arthritis and in C3a and C5a generation in vitro |
Clin. Exp. Immunol. |
159 |
100-108 |
2010 |
Mus musculus |
19843088 |
| 3.4.21.43 | 680169 |
Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway |
Int. Immunol. |
19 |
141-149 |
2007 |
Homo sapiens |
17182967 |
| 3.4.21.43 | 683831 |
Dissecting the regions of virion-associated Kaposis sarcoma-associated herpesvirus complement control protein required for complement regulation and cell binding |
J. Virol. |
80 |
4068-4078 |
2006 |
Homo sapiens |
16571823 |
