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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
2.5.1.66
742159
Heterologous production of clavulanic acid intermediates in Streptomyces venezuelae
Biotechnol. Bioprocess Eng.
22
359-365
2017
Streptomyces clavuligerus
-
2.5.1.66
760210
Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus
Synth. Syst. Biotechnol.
2
39-48
2017
Streptomyces clavuligerus
29062960
2.5.1.66
676072
An rplKDelta29-PALG-32 mutation leads to reduced expression of the regulatory genes ccaR and claR and very low transcription of the ceaS2 gene for clavulanic acid biosynthesis in Streptomyces clavuligerus
Mol. Microbiol.
61
758-770
2006
Streptomyces clavuligerus
16803595
2.5.1.66
721360
Carboxyethylarginine synthase genes show complex cross-regulation in Streptomyces clavuligerus
Appl. Environ. Microbiol.
79
240-249
2013
Streptomyces clavuligerus
23104404
2.5.1.66
654288
Clavulanic acid, a beta-lactamase inhibitor: biosynthesis and molecular genetics
Appl. Microbiol. Biotechnol.
54
467-475
2000
Streptomyces clavuligerus
11092620
2.5.1.66
656267
Crystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathway
J. Biol. Chem.
279
5685-5692
2004
Streptomyces clavuligerus
14623876
2.5.1.66
655778
Origin of the b-lactam carbons in clavulanic acid from an unusual thiamine pyrophosphate-mediated reaction
J. Am. Chem. Soc.
121
9223-9224
1999
Streptomyces clavuligerus
-
2.5.1.66
702059
Structural and mechanistic studies on N(2)-(2-carboxyethyl)arginine synthase
Biochem. Biophys. Res. Commun.
385
512-517
2009
Streptomyces clavuligerus
19477162
2.5.1.66
655886
The paralogous pairs of genes involved in clavulanic acid and clavam metabolite biosynthesis are differently regulated in Streptomyces clavuligerus
J. Bacteriol.
186
6286-6297
2004
Streptomyces clavuligerus
15342599
2.5.1.66
654207
Two sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus
Antimicrob. Agents Chemother.
48
930-939
2004
Streptomyces clavuligerus
14982786
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