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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
1.5.1.15
760434
A role for glutamine 183 in the folate oxidative half-reaction of methylenetetrahydrofolate reductase from Escherichia coli
Arch. Biochem. Biophys.
642
63-74
2018
Escherichia coli
29407039
1.5.1.15
756337
Crystal structure of the emerging cancer target MTHFD2 in complex with a substrate-based inhibitor
Cancer Res.
77
937-948
2017
Homo sapiens
27899380
1.5.1.15
756334
Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
Cancer Metab.
5
11
2017
Homo sapiens
29225823
1.5.1.15
765009
Monomeric NADH-oxidizing methylenetetrahydrofolate reductases from Mycobacterium smegmatis lack flavin coenzyme
J. Bacteriol.
202
e00709-19
2020
no activity by Mycobacterium smegmatis MSMEG_6664
32253341
1.5.1.15
765009
Monomeric NADH-oxidizing methylenetetrahydrofolate reductases from Mycobacterium smegmatis lack flavin coenzyme
J. Bacteriol.
202
e00709-19
2020
no activity by Mycobacterium smegmatis MSMEI_6484
32253341
1.5.1.15
765009
Monomeric NADH-oxidizing methylenetetrahydrofolate reductases from Mycobacterium smegmatis lack flavin coenzyme
J. Bacteriol.
202
e00709-19
2020
Mycolicibacterium smegmatis
32253341
1.5.1.15
765009
Monomeric NADH-oxidizing methylenetetrahydrofolate reductases from Mycobacterium smegmatis lack flavin coenzyme
J. Bacteriol.
202
e00709-19
2020
Mycolicibacterium smegmatis ATCC 700084
32253341
1.5.1.15
765840
Mthfd2 modulates mitochondrial function and DNA repair to maintain the pluripotency of mouse stem cells
Stem Cell Reports
15
529-545
2020
Mus musculus
32679066
1.5.1.15
757773
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
Nat. Commun.
9
2292
2018
Homo sapiens
29895827
1.5.1.15
392084
Activity of an NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase in normal tissue, neoplastic cells, and oncogene-transformed cells
Arch. Biochem. Biophys.
283
367-371
1990
Bos taurus
2275549
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