EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   1.14.14.55 | 744769 |
Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway |
Drug Metab. Dispos. |
30 |
1368-1371 |
2002 |
Homo sapiens |
12433805 |
| 1.14.14.55 | 744608 |
Evidence for involvement of human CYP3A in the 3-hydroxylation of quinine |
Br. J. Clin. Pharmacol. |
43 |
245-252 |
1997 |
Homo sapiens |
9088578 |
| 1.14.14.55 | 745448 |
Influence of a Nigerian honey on CYP3A4 biotransformation of quinine in healthy volunteers |
J. Clin. Pharm. Ther. |
40 |
545-549 |
2015 |
Homo sapiens |
26177778 |
| 1.14.14.55 | 744611 |
Is quinine a suitable probe to assess the hepatic drug-metabolizing enzyme CYP3A4? |
Br. J. Clin. Pharmacol. |
54 |
643-651 |
2002 |
Homo sapiens |
12492613 |
| 1.14.14.55 | 744609 |
Metabolic interactions of selected antimalarial and non-antimalarial drugs with the major pathway (3-hydroxylation) of quinine in human liver microsomes |
Br. J. Clin. Pharmacol. |
44 |
505-511 |
1997 |
Homo sapiens |
9384469 |
| 1.14.14.55 | 744749 |
Ontogeny of hepatic microsomal 3-hydroxylation of quinine in Adelie Penguins |
Comp. Biochem. Physiol. C |
138 |
53-58 |
2004 |
Pygoscelis adeliae |
15313446 |
| 1.14.14.55 | 744838 |
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man |
Eur. J. Clin. Pharmacol. |
59 |
23-28 |
2003 |
Homo sapiens |
12743670 |
| 1.14.14.55 | 744743 |
The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine in vivo |
Clin. Pharmacol. Ther. |
66 |
454-460 |
1999 |
Homo sapiens |
10579472 |
| 1.14.14.55 | 706089 |
4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians |
Pharmacogenet. Genomics |
18 |
201-208 |
2008 |
Homo sapiens |
18300941 |
| 1.14.14.55 | 676312 |
CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population |
Pharmacogenet. Genomics |
16 |
637-645 |
2006 |
Homo sapiens |
16906018 |
