EC Number   |
Reaction Type |
Reference |
|---|
   4.2.99.18 | beta-elimination |
- |
171803, 648627, 648629, 648630, 690473, 694866 |
| 4.2.99.18 | endonuclease activity |
- |
-, 694298, 694326 |
| 4.2.99.18 | endonuclease reaction |
- |
678781, 679493, 680830, 690472, 690474, 691026, 691620, 691638, 692463, 692847, 692875, 693225, 693581, 693643, 693644, 694162, 694298, 694466, 694866 |
| 4.2.99.18 | endonuclease reaction |
an essential protein that functions as part of base excision repair to remove mutagenic and cytotoxic abasic sites from DNA |
692773 |
| 4.2.99.18 | endonuclease reaction |
APE1 has dual activities, a strong endonuclease activity, and a weak exonuclease-phosphodiesterase activity |
679468 |
| 4.2.99.18 | endonuclease reaction |
associative one-step hydrolytic mechanism |
691013 |
| 4.2.99.18 | endonuclease reaction |
cleavage of the phosphodiester either 5' or 3' to an apurinic/apyrimidinic site |
694593 |
| 4.2.99.18 | endonuclease reaction |
the protein has AP endonuclease and 3'-5' exonuclease activity |
679496 |
| 4.2.99.18 | exonuclease reaction |
- |
691026 |
| 4.2.99.18 | hydrolysis |
- |
680830 |
