EC Number |
Reaction |
Reference |
---|
6.4.1.2 | ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA |
catalytic regions analysis |
-, 664193 |
6.4.1.2 | ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA |
molecular surface of the active site of the carboxyltransferase domain |
666936 |
6.4.1.2 | ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA |
non-ordered ter ter mechanism |
37629 |
6.4.1.2 | ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA |
ordered bi bi uni uni ping-pong mechanism |
37586 |
6.4.1.2 | ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA |
ordered mechanism |
37608 |
6.4.1.2 | ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA |
substrate specificity, catalytic mechanism, and structural features |
661098 |
6.4.1.2 | ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA |
the enzyme is bifunctional exhibiting both acetyl-CoA carboxylase and propionyl-CoA carboxylase, EC 6.4.1.3, activities |
-, 662786 |
6.4.1.2 | ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA |
the enzyme proceeds through a hybrid (two-site) random Ter Ter mechanism, one that likely involves a two-step reaction at the biotin carboxylase domain |
702459 |
6.4.1.2 | ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA |
two-step reaction mechanism, structure-activity relationship |
664564 |