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Results 1 - 2 of 2
EC Number Reaction Commentary Reference
Show all pathways known for 6.3.2.1Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.1ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate bi uni uni bi ping pong mechanism 978
Show all pathways known for 6.3.2.1Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.1ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate the enzyme catalyzes the ATP-dependent condensation of pantoate with beta-alanine via a pantoyl adenylate intermediate and follows a bi uni uni bi ping pong kinetic mechanism. The Mg2+ dependent reaction involves two sequential steps. Initially binding of ATP with pantoate, leads to formation of pantoyl adenylate and release of diphosphate. Second step involves nucleophilic attack by beta-alanine on the active carbonyl group of pantoyl adenylate and subsequent release of AMP and pantothenate -, 746489
Results 1 - 2 of 2