EC Number   |
Reaction |
Reference |
|---|
    6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
- |
- |
| 6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
ATP is the first substrate to enter into the reaction sequence and prolyl-tRNA is the last product to dissociate from the enzyme |
175 |
| 6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
bi uni ping pong mechanism |
175 |
| 6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
class II synthetases are limited by a step prior to aminoacyl transfer |
675395 |
| 6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
dual substrate specificity |
653591 |
| 6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
enzyme with dual substrate specificity which utilizes L-proline and L-cysteine as substrates, discriminating mechanism |
651296 |
| 6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
induced fit substrate recognition, reaction mechanism, proline binding site structure |
652859 |
| 6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
one tRNA binds per dimeric enzyme, only 50% of active sites are active |
661767 |
| 6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
substrate binding mechanism, the two bases G35 and G36 are sufficient to uniquely identify the cognate tRNAPro |
-, 653918 |
| 6.1.1.15 | ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro |
the C-terminal extremity folds back into the active site |
650975 |
