EC Number   |
Reaction |
Reference |
|---|
    4.2.3.124 | D-glucose 6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate |
- |
- |
| 4.2.3.124 | D-glucose 6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate |
catalyric reaction mechanism and substrate specificity, overview |
-, 719108 |
| 4.2.3.124 | D-glucose 6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate |
DOIS catalyzes the multi-step and direct cyclization reaction of G-6-P consisting five crucial transformations, which include the initial NAD+-dependent dehydrogenation at C-4, the elimination of a phosphate from C-5 and C-6, the hydride comeback to C-4 to form a cyclic enol ether, and the finial aldol-type intramolecular condensation between C-6 and C-1 |
719040 |
| 4.2.3.124 | D-glucose 6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate |
reaction and stereochemical mechanisms, overview |
719279 |
| 4.2.3.124 | D-glucose 6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate |
reaction mechanism of the multistep reaction, stereochemistry of the phosphate elimination reaction, proceeding through syn-elimination assisted by Glu 243, and the cyclization, an aldol condensation that proceeds via a boat conformation, overview |
-, 721011 |
| 4.2.3.124 | D-glucose 6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate |
reaction mechanism, overview |
-, 719667, 719668, 720302 |
| 4.2.3.124 | D-glucose 6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate |
the reaction mechanism includes oxidation of C-4, beta-elimination of phosphate, reduction of C-4, ring opening, and intramolecular aldol cyclization. Completely conserved E243 of BtrC is catalytically involved in the phosphate elimination step |
719072 |
