EC Number   |
Reaction |
Reference |
|---|
    4.2.1.33 | (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate |
overall reaction |
- |
| 4.2.1.33 | (2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H2O |
(1a) |
- |
| 4.2.1.33 | (2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H2O |
equilibrium concentration ratios |
5661 |
| 4.2.1.33 | (2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H2O |
feedback regulation by leucine |
5662 |
| 4.2.1.33 | (2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H2O |
mechanism, equilibrium in vitro favors reaction opposite the direction of leucine biosynthesis |
5659 |
| 4.2.1.33 | (2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H2O |
stoichiometry of reaction, enzyme also hydrates 2-isopropylmaleate to 3-hydroxy-4-methyl-3-carboxypentanoate, interconversion between the 2 isomers |
5658 |
| 4.2.1.33 | (2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H2O |
transcriptional feedback regulation by leucine |
5663 |
| 4.2.1.33 | 2-isopropylmaleate + H2O = (2S)-2-isopropylmalate |
(1b) |
- |
