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Results 1 - 4 of 4
EC Number Reaction Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.46broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein enzyme is an aspartic protease but is atypical in containing a C-terminal membrane-spanning domain 638908
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.46broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein mechanism for enzyme regulation 638914
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.46broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein memapsin 1 and 2 have overlapping yet distinct sequence preference 638909
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.46broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein suggested to be the major "beta-secretase" responsible for the cleavage of the beta-amyloid precursor protein to form the amyloidogenic beta-peptide that is implicated in the pathology of Alzheimer's disease 638909
Results 1 - 4 of 4