EC Number |
Reaction |
Reference |
---|
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
- |
- |
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
also hydrolyses 1,4-beta-D-glycosidic linkages between N-acetyl-galactosamine or N-acetylgalactosamine sulfate and glucuronic acid in chondroitin, chondroitin 4- and 6-sulfates, and dermatan |
171393, 649321, 650500, 650509, 651288 |
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
endoglycosidase with exoglycosidase activity |
649440 |
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
enzyme is a beta-1,4-glucosidase, substrate binding groove, enzyme-substrate complex structure, catalytic groups and reaction mechanism |
653937 |
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
hydrolase mechanism |
652643 |
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
reaction mechanism and three-dimensional structure |
664596 |
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
reaction mechanism and three-dimensional structure, catalytic residue is Glu113, substrate positioning residues, overview |
664596 |
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
reaction mechanism and three-dimensional structure, catalytic residue is Glu149, substrate positioning residues, overview |
664596 |
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
reaction mechanism and three-dimensional structure, catalytic residues of isozymes Hyal1-Hyal4 are Glu131, Glu135, Glu129, and Glu147, respectively, substrate positioning residues, active site structure of isozymes, overview |
664596 |
3.2.1.35 | hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide |
specifically hydrolyses 1,4-beta-D-glycosidic linkages, reaction mechanism, simulation of product formation process, active site |
649735 |