EC Number |
Reaction |
Reference |
---|
3.2.1.183 | UDP-N-acetyl-alpha-D-glucosamine + H2O = N-acetyl-D-mannosamine + UDP |
- |
- |
3.2.1.183 | UDP-N-acetyl-alpha-D-glucosamine + H2O = N-acetyl-D-mannosamine + UDP |
catalytic and regulatory mechanisms |
748227 |
3.2.1.183 | UDP-N-acetyl-alpha-D-glucosamine + H2O = N-acetyl-D-mannosamine + UDP |
the epimerase reaction is shown to proceed with a retention of stereochemistry at C-1, and the loss of UDP is found to occur via a C-O bond cleavage process. Results support a mechanism involving an anti-elimination of UDP followed by the syn-hydration of 2-acetamidoglucal |
651592 |
3.2.1.183 | UDP-N-acetyl-alpha-D-glucosamine + H2O = N-acetyl-D-mannosamine + UDP |
the mechanism is proposed to involve an anti elimination of UDP to form 2-acetamidoglucal as an intermediate, followed by the syn addition of water |
-, 661102 |