EC Number   |
Reaction |
Reference |
|---|
    3.1.4.4 | a phosphatidylcholine + H2O = choline + a phosphatidate |
acts also on other phosphatidyl esters |
135426 |
| 3.1.4.4 | a phosphatidylcholine + H2O = choline + a phosphatidate |
catalytic mechanism, PLD uses a ping-pong type of reaction through the formation of a covalent phosphatidyl-enzyme intermediate, structure-function relationship, and substrate recognition and specificity, overview |
707556 |
| 3.1.4.4 | a phosphatidylcholine + H2O = choline + a phosphatidate |
catalytic mechanisms of PLD isozymes, overview |
730316 |
| 3.1.4.4 | a phosphatidylcholine + H2O = choline + a phosphatidate |
general reaction mechanism through an SN2-type associative pathway for phospholipase D-catalyzed hydrolysis of phospholipids, the formation of the phosphohistidine intermediate involves the conserved histidine 167 of the N-terminal HKD domain, overview |
708115 |
| 3.1.4.4 | a phosphatidylcholine + H2O = choline + a phosphatidate |
mechanism |
-, 649327, 650153, 653086 |
| 3.1.4.4 | a phosphatidylcholine + H2O = choline + a phosphatidate |
mechanism, structural requirements of substrate |
652945 |
| 3.1.4.4 | a phosphatidylcholine + H2O = choline + a phosphatidate |
mode of substrate binding, the catalysis proceeds via two-step reaction with the formation of phosphatidyl-enzyme intermediate. Both of the two catalytic His residues are critical in the reaction course, where one acts as a nucleophile, while the other functions as a general acid/base, reaction cycle overview |
730075 |
| 3.1.4.4 | a phosphatidylcholine + H2O = choline + a phosphatidate |
the catalysis proceeds via two-step reaction with the formation of phosphatidyl-enzyme intermediate. Both of the two catalytic His residues are critical in the reaction course, where one acts as a nucleophile, while the other functions as a general acid/base, reaction cycle overview |
-, 730075 |
