EC Number   |
Reaction |
Reference |
|---|
    2.3.3.8 | ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA |
citrate cleavage is of the si-type |
488189 |
| 2.3.3.8 | ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA |
cleaves citrate with inversion of configuration |
488204 |
| 2.3.3.8 | ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA |
double-displacement mechanism with a phosphoenzyme intermediate |
488186 |
| 2.3.3.8 | ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA |
in the absence of the CoA acceptor, the enzyme contains a freely diffusible highly reactive intermediate, with similar properties to other high-free-energy phosphotransfer intermediates such as aminoacyl adenylates |
488213 |
| 2.3.3.8 | ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA |
mechanism |
33352, 488213 |
| 2.3.3.8 | ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA |
ordered mechanism where the phosphate group of ATP is first covalently bound to the His273 catalytic residue, and subsequently transferred to the citrate molecule to form citryl phosphate |
488225 |
